Isaiah now turns this rich man's dream of vast holdings with a single owner into a curse. Where the pride of men causes them to accumulate land and evict the previous owners, the Lord now tells them that they will indeed be alone, but not because of their accumulations, but rather because of the desolation from the wrath of the Lord's destruction. Lands and even cities will be without inhabitant.
Where the previous verse extrapolated on the wish of the rich, this verse turns that wish to terror. The literary linkage between the two verses reinforces the culpability of the men of Judah.